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Design & development of novel synthetic routes for various chemical entities and Active Pharmaceutical Ingredients.
Collaborative research for cutting edge solutions in chemistry.
Metabolomics and pathway engineering of medicinal and aromatic plants. Genetic enhancement of potential biofuel plants.
Mode of action studies, target site identification of new molecules using drosophila genetics.
Metabolic pathway analysis, Protein modeling, Drug protein interaction, Molecular targets and QSAR.
Exploration of traditionally used medicinal plants for newer compounds with hepatoprotective, immuno-modulatory and other pharmacological properties. Development of processes and products from edible plants with anti-obesity and anti-oxidant properties for safe consumption as food supplement
Development of inputs for organic crop production and protection. Field evaluation of package of practices in organic farming. Capacity building & farm to shelf integration.
Strain improvement and process engineering development to enhance the energy efficiency and productivity of extra neutral alcohol. Development of fermented food supplements for the wellness segment.
search for ecofriendly biopesticides from Neem and other plants.
Environmentally safe, biodegradable chemicals for industrial and agricultural use.
Biofuel is a renewable fuel which can be an alternative to or an addition to petroleum diesel with multitude of environmental benefits. Various oil seed plants suited to wide agro climatic conditions are being explored as the sources of future fuels, as the fossil fuels may soon be exhausted. Jatropha carcus is a promising energy crop with more than 35% oil content and its innate ability to be used in modern combustion engines. Jatropha is an environment friendly plant and grows luxuriously in the Indian subcontinent as a fence weed. Commercially Jatropha oil is trans esterified and used as a 10-20% mixture with fossil fuels in the vehicular engines. We at VMSRF are aiming to molecularly alter the seed oil composition and generate elite jatropha oil, which can be used in the modern engines without any blending with petroleum fuel. Altering the seed oil composition will aid in achieving the desired density, dynamic viscosity, heat capacity & boiling point and heat of combustion. The lower dynamic viscosity and higher heat of combustion is mainly attributed by medium and short chain fatty acids in the seed oil. Metabolic engineering of the fatty acid biosynthetic pathway to produce a grater amount of medium chain fatty acids is being undertaken. Jatropha plant sets to fruiting in 3rd year and seeds can be collected for as long as 50 years. It hence becomes imperative to develop molecular markers for identification of elite clones in the existing germplasm. Molecular markers are being developed for the high oil yielding jatropha varieties to tap the elite clones in juvenile stage and make the jatropha plantation more economically viable for farmers. |
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